Name | Ethyl isocyanoacetate |
Synonyms | Isocyanoacetate 2-isocyanobutanoate Ethyl isocyanoacetate Ethyl 2-isocyanoacetate 2-Oxo-2-ethoxyethyl isocyanide Ethoxycarbonylmethyl isocyanide ethyl isocyanoacetate 2999-46-4 Isocyanoacetic acid ethyl ester (2-Oxo-2-ethoxyethyl) isocyanide Acetic acid, isocyano-, ethyl ester |
CAS | 2999-46-4 |
EINECS | 221-077-9 |
InChI | InChI=1/C5H7NO2/c1-3-4(6-2)5(7)8/h4H,3H2,1H3,(H,7,8)/p-1 |
Molecular Formula | C5H7NO2 |
Molar Mass | 113.11 |
Density | 1.035 g/mL at 25 °C (lit.) |
Boling Point | 194-196 °C (lit.) |
Flash Point | 184°F |
Water Solubility | Miscible with organic solvents. Slightly miscible with water. |
Vapor Presure | 61.7Pa at 25℃ |
Appearance | Liquid |
Color | Clear amber to dark brown |
Exposure Limit | NIOSH: IDLH 25 mg/m3 |
BRN | 3588613 |
Storage Condition | 2-8°C |
Sensitive | Moisture & Light Sensitive |
Refractive Index | n20/D 1.418(lit.) |
Hazard Symbols | Xn - Harmful |
Risk Codes | R20/22 - Harmful by inhalation and if swallowed. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S24/25 - Avoid contact with skin and eyes. |
UN IDs | UN 2810 6.1/PG 3 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8-9-21 |
HS Code | 29299090 |
Hazard Class | 6.1 |
Packing Group | III |
LogP | 0.91 at 25℃ |
properties | light yellow liquid, slightly soluble in water and lye, miscible in ethanol and ether. |
poisoning symptoms | isocyanoacetate mild poisoning, will appear dizziness, headache, chest tightness, shortness of breath and other symptoms, moderate poisoning will appear cramps and other symptoms, severe poisoning, can cause lightning-like death, that is, instantaneous death. |
hazardous characteristics | isocyanoacetate belongs to cyanide series, belongs to dangerous chemicals, is toxic, is forbidden, and needs to be sealed and stored. In case of acid, water, high temperature, etc., the substance will release hydrogen cyanide gas, which is highly toxic. Once inhaled, cyanide ions will be formed in the body. Cyanide ions inhibit the respiration of human cells and hinder the electron transfer of cells, thus causing asphyxia in cells and causing damage to the nervous system. |
Uses | Intermediates in organic synthesis and pharmaceutical synthesis, which can be used to synthesize flumazenil (flumazenil/flumazenil). Biochemical research |